1. In humans, the adult skull is normally made up of 22 bones.
2. The skull is a complex structure; its bones are formed both by intramembranous and endochondral ossification.
3. As growth occurs, many of these bony elements gradually fuse together into solid bone (for example, the frontal bone).
4. There are five sutures: the frontal suture, sagittal suture, lambdoid suture, coronal suture, and squamosal suture.
5. Normally the skull protects the brain from damage through its hard unyieldingness; the skull is one of the most durable substances found in nature.
6. Dating back to Neolithic times, a skull operation called trepanation was sometimes performed.
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